Mykelti Williamson and Justin Lazard are a pair of astronauts who make the first successful manned mission to Mars. Lazard's character gets infected by an alien and slowly begins to mutate. When they get back to Earth all he has on his mind is to have sex with Henstridge!

Middle-aged, sexually repressed Sylvia Stickles is the subject of this John Water's film, set in North Baltimore. She refuses to have sex with her husband, Vaughn Stickles, and keeps her overly-endowed daughter, Caprice, locked in her room, while she serves home detention for moral depravity charges. Sylvia, together with her mother Big Ethel, lead a group calling themselves "neuters" that promotes decency on Harford Road. When Sylvia is accidentally hit on the head by a lawnmower hanging out of...